Three New Cytotoxic Polyhydroxysteroidal Glycosides from Starfish Craspidaster hesperus
نویسندگان
چکیده
Three new polyhydroxysteroidal glycosides, hesperuside A (1), B (2), and C (3), as well as a known novaeguinoside A (4), were isolated from the ethanol extract of starfish Craspidaster hesperus collected from the South China Sea. Their structures were elucidated by extensive spectroscopic methods and chemical evidence. The compounds 1-3 present unprecedented carbohydrate chain 3-O-methyl-β-d-galactopyranose, which differ from each other in the side chains. These compounds exhibited cytotoxicity against human tumor cells BEL-7402, MOLT-4, and A-549 in vitro.
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عنوان ژورنال:
دوره 14 شماره
صفحات -
تاریخ انتشار 2016